chancre
‘a dull red, hard, insensitive lesion that is the first manifestation of syphilis’
Lexical development traced from the Tamil root:
E. shanker, schanker, shancre, shankre < F. chancre ‘cancer’ < Lat. cancer ‘a crab has a hard shell, malignant tumor’ < Gk. karkinos < karkro- < kr < kar- < Tamil kaṭu